Stability and Formulations: 70 drugs studies for
stability in Paddock's oral compounding vehicles
The American Journal of Health-System Pharmacy has published a series of six studies involving Paddock Laboratories' compounding vehicles -- Ora-Plus®, Ora-Sweet® and Ora-Sweet® SF.
"(T)he purpose of these studies were to determine the compatibility and stability of drugs commonly prescribed for use in oral liquid dosage forms but not commercially available as such. Pharmacists need this information to make professional decisions about vehicle selection and the assignment of expiration dates."
"Stability of acetazolamide, allopurinol, azathioprine, clonazepam and flucytosine in extemporaneously compounded oral liquids", Am J Health-Syst Pharm, Vol 53 Issue 16, August 15, 1996, pages 1944 - 1949.
"Stability of ketoconazole, metolazone, metronidazole, procainamide hydrochloride, and spironolactone in extemporaneously compounded oral liquids", Am J Health-Syst Pharm, Vol 53 Issue 17, September 1, 1996, pages 2073 - 2078.
"Stability of baclofen, captopril, diltiazem hydrochloride, dipyridamole, and flecainide acetate in extemporaneously compounded oral liquids", Am J Health-Syst Pharm, Vol 53 Issue 18, September 15, 1996, pages 2179 - 2184.
"Stability of labetalol hydrochloride, metaprolol tartrate, verapamil hydrochloride, and spironolactone with hydrochlorothiazide in extemporaneously compounded oral liquids", Am J Health-Syst Pharm, Vol 53 Issue 19, October 1, 1996, pages 2304 - 2309.
"Stability of bethanechol chloride, pyrazinamide, quinidine sulfate, rifampin and tetracycline hydrochloride in extemporaneously compounded oral liquids". Am J Health-Syst Pharm, Vol 55 Issue 17, September 1, 1998, pages 1804-1809.
"Stability of alprazolam, chloroquine phosphate, cisapride, enalapril maleate and hydralazine hydrochloride in extemporaneously compounded liquids". Am J Health-Syst Pharm, Vol 55 Issue 18, September 15, 1998, pages 1915-1920.
Check out the Secundem Artem issues containing these stability studies of extemporaneously prepared oral formulations using our Ora's.
 Vol 5 No 4: Part I
Vol 6 No 1: Part II
Vol 6 No 2: Part III
Vol 14 No 1: Part IV
Vol 14 No 3: Part V
Bibliography - List of over 60 published extemporaneously oral liquid
stability studies
Comprehensive data sheets on our compounding actives and vehicles with formulations are available. Order product from your wholesaler or direct from Paddock Laboratories.
Call us at 1-800-328-5113.
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